
【个人简历】
乐秀秀,中共党员,博士,毕业于中南大学化学化工学院,主要研究方向为荧光探针及光敏剂的合成与应用。
【教学工作】
主讲课程为《营养学基础与应用》、《有机化学实验》、《药物分析化学》和《无积极分析化学实验》。
【教研项目】
(1) 湖北省自然科学基金计划(青年B类项目):同时检测NADPH和HClO荧光探针用于非酒精性脂肪肝的成像研究。(2025.3.30,主持)
(2) 湖北省教育厅科学研究计划项目:比率型荧光探针用于环境和食品中H2S的快速检测。(2025.6.30,主持)
(3)国家自然科学基金委员会(面上项目): 基于单光源激发的H2O2和HClO双光子比率型荧光探 针的构建及在生物中的应用, (2022-01-01 至 2025-12-31 )资助期满, 参与。
【学术成果】
(1) Yue, X.; Wang, J.; Han, J.; Wang, B and Song, X. A dual-ratiometric fluorescent probe for individual and continuous detection of H2S and HClO in living cells. Chemical Communications 2020, 56, 2849.
(2) Yue, X.; Chen, J.; Chen, W.; Wang, B.; Zhang, H and Song, X. An endoplasmic reticulum-targeting fluorescent probe for discriminatory detection of Cys, Hcy and GSH in living cells. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 2021, 250, 119347.
(3) Yue, X.; Xu, J.; Liu, X.; Song, X and Foley, J. W. Improved synthetic method of Benzo[a]pheno- selenazinium phototherapeutic agents. Dyes and Pigments 2021, 188, 109154.
(4) Zhang, H.; ? Yue, X.;? Li, W.; Chen, W.; Wang, Y.; Li, X.; Ye, Y and Song, X. Selective and discriminative fluorescence sensing ofCys, Hcy, GSH and H2S with concise and distinct signals. Sensors and Actuators B: Chemical 2021, 331, 129394.
(5) Yue, X.; Yang, Y.; Lan, M.; Li, K and Wang, B. Dual-ratiometric fluorescence sensing and real-time detection of HOCl and NQO1 using a single fluorescent probe under one-wavelength excitation. Analytica Chimica Acta 2022, 1224, 340242.
(6) Yue, X.; Wang, B.; Lan, M.; Fan, J.; Song, X and Foley. J. W. Three birds one stone: an enzyme-activatable theragnostic agent for fluorescence diagnosis, photodynamic and inhibitor therapies. Chemical Communications 2023, 59, 7060.
(7) Yue, X.; Guo, T.; Zhang, H.; Wang, B.; Lan, M and Song, X. An estradiol-functionalized red-emissive photosensitizer for enhanced and precise photodynamic therapy of breast cancers.
(8) Chen, W.; Yue, X.; Zhang, H.; Li, W.; Zhang, L.; Xiao, Q.; Huang, C.; Sheng, J.; Song, X. Simultaneous detection of glutathione and hydrogen polysulfides from different emission channels. Analytical chemistry 2017, 89, 12984.
(9) Chen, W.; Yue, X.; Li, W.; Hao, Y.; Zhang, L.; Zhu, L.; Sheng, J.; Song, X. A phenothiazine coumarin-based red emitting fluorescent probe for nanomolar detection of thiophenol with a large Stokes shift. Sensors and Actuators B: Chemical 2017, 245, 702.
(10) Yue, X.; Li, W.; Chen, W.; Zhang, L.; Li, G.; Sheng, J. A dual-response naphthofluorescein-based fluorescent probe for multiple-channel imaging of cysteine/homocysteine in living cells. Tetrahedron Letters 2018, 59, 2232.
(11) Chen, W.; Yue, X.; Sheng, J.; Li, W.; Zhang, L.; Su, W.; Huang, C.; Song, X. Rational development of a highly selective ratiometric fluorescent probe for hydrogen polysulfides. Sensors and Actuators B: Chemical 2018, 258, 125.
(12) 专利:一种具有双比值识别过氧化氢和次氯酸的荧光探针(2021-05-25)。

